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In Moldova, the average BOD and ammonium concentration in rivers show similar patterns over the time period 1992-2017, with declining levels until 1997-1998 then fluctuating higher levels, and finally returning to similar levels to the start of the time period. Ammonium concentrations were highest between 2001-2004, while BOD was highest around 2003-2008. However, the increases in pollution can be attributed to sites in the Dniester river basin. For the sites in the Prut river basin and the two sites on the Danube and its tributary (Cogîlnic) ammonium concentrations generally decreased over time and BOD levels were stable or slightly decreasing.