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Pesticides input from diffuse sources can have impacts to aquatic communities, if they are directly exposed to pesticides inflow from farmland via erosion or indirectly through trophic chain (Hasenbein, et al., 2016; Maksymiv, 2015). Pesticides can also threaten human health, if contaminated surface waters or groundwater are used for drinking water supply. Furthermore, aquatic communities are exposed to mixtures of different pesticide substances. The knowledge on their combined effects of these mixtures to the aquatic environment is rare (Mohaupt,, Völker,, Altenburger,, Birk,, Kirst,, Kühnel,, Semeradova, et al., 2020).