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Clearly, responses and adaptation measures differ, depending on the issues and priorities of each region and are designed to either increase supply (supply–side strategies) or reduce demand (demand–side adaptation strategies). The effectiveness of the response measures is difficult to assess, as it relates to the inherent complexity of water scarcity phenomenon, which has its roots both on natural and anthropogenic drivers, which in turn result in pressures, adversely changing the state, and causing multiple impacts on the environment, economy and society.