Post a comment on the text below

In human pharmacology and toxicology, the concept of mixture toxicity effects of many different substances which are applied at the same time is known. Adopting and applying this concept seems to be one possible solution to address contamination by pesticides in the environment. One published mixture approach is based on the Toxic Unit (TU) system. This TU is recommended to be used for risk assessment in the aquatic ecosystem. The TU is defined by the ratio of the concentration of a substance to its actual toxicity. Behind that concept stands the idea that the toxicity of a mixture of many similar acting substances can be assessed by adding up each substance effect concentration. This approach is most often known in scientific literature as the “concentration addition (CA)” approach.